High blood pressure is a serious problem worldwide, affecting 1.4 billion people in 2024. Now researchers have developed a new injection, Gilbesiran ...read more

High blood pressure is a rapidly growing serious health problem worldwide. Data from the World Health Organization (WHO) shows that in 2024, 1.4 billion people worldwide aged 30-79 years old had hypertension. This figure represents approximately 33% of the total population in this age group. Health experts say that the problem of hypertension is also increasing among children, which can make them victims of many chronic diseases at an early age.

Doctors advise patients suffering from hypertension to take medicines regularly, so that they can be protected from problems caused by increased blood pressure like heart attack, stroke, kidney and eye problems.

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Patients may have to take these medications for life. Researchers have found an alternative to blood pressure medications. In a recent report, researchers have stated that soon you will be able to control your blood pressure without taking medication daily. An injection is being discussed as an alternative, which, by taking it just twice a year instead of pills, will help you control your blood pressure. Experts are seeing this injection, called Gilebesiran, as an effective solution for the future.

The risk of hypertension and many serious problems will be reduced

The Lancet journal has provided information about the benefits of this injection to BP patients. Researchers say that this discovery can completely change the way hypertension is managed, especially at a time when despite decades of existing medicines, the number of high blood pressure patients is increasing worldwide. It is believed that Gilbesiran injection can be helpful in controlling hypertension for a long time. It can also help in reducing the risk of heart attack and stroke along with kidney and eye problems.

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How will this injection work?

Currently, it is in its late-stage global trials. This twice-yearly injection can control high blood pressure. Developed by Roche and Alnylam Pharmaceuticals, Gilebesiran injection will need to be administered twice a year. It uses small interfering RNA (iRNA) technology to reduce the production of angiotensinogen in the liver. By slowing the production of angiotensinogen, this injection can keep blood pressure under control for up to six months.

What do experts say?

Experts say initial trials suggest this injection may be effective, but researchers caution that hypertension is a lifelong disease and this therapy is still under clinical investigation. Its effectiveness in replacing standard treatments, such as daily medications, cannot be determined at this time. According to a global analysis published in The Lancet Child & Adolescent Health journal, the incidence of high blood pressure in children and adolescents has nearly doubled in the past two decades, increasing the risk of heart disease .

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